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Biological activity of amide derivatives of lysine.
- Source :
-
Acta poloniae pharmaceutica [Acta Pol Pharm] 2008 May-Jun; Vol. 65 (3), pp. 377-81. - Publication Year :
- 2008
-
Abstract
- Five substituted amides of lysine with the general formula: X-Lys-NH-Y, where X= acetyl or ethoxycarbonyl, Y= cyclohexyl, benzyl, hexyl or cadaverine residue were synthesised and their effects on fibrinolytic activity of plasmin, clotting activity of thrombin and amidolytic activities of both enzymes were examined.
- Subjects :
- Amides pharmacology
Blood Coagulation drug effects
Blood Coagulation physiology
Fibrinolysis drug effects
Fibrinolysis physiology
Lysine pharmacology
Structure-Activity Relationship
Amides chemical synthesis
Fibrinolysin antagonists & inhibitors
Lysine analogs & derivatives
Thrombin antagonists & inhibitors
Subjects
Details
- Language :
- English
- ISSN :
- 0001-6837
- Volume :
- 65
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Acta poloniae pharmaceutica
- Publication Type :
- Academic Journal
- Accession number :
- 18646558