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[Plasma MHPG, peripheral noradrenergic marker and hormonal plasma levels of cortisol-T3-T4-TSH in depressive syndromes].
- Source :
-
L'Encephale [Encephale] 1991 May-Jun; Vol. 17 (3), pp. 203-11. - Publication Year :
- 1991
-
Abstract
- Based on the hypocatecholaminergic hypothesis in the depressive syndromes, this survey on 30 depressed patients compared to 21 control patients, attempts to state exactly the potential interactions between the noradrenergic system and the hypothalamic-pituitary-adrenal and hypothalamic-pituitary-thyroid neuroendocrine axis. The biological indices used during this survey are: total plasmatic MHPG, the basic plasmatic cortisol, the thyroid hormones T3, T4, free T4, and the TSH. The results of this survey reveal a significative increase of the basic plasmatic cortisol among the depressed patients, including dysthymics, a decrease of the plasmatic MHPG during major depressions, and a significant fall of the total T3 among depressed men, as well as some correlations between the different axes, the interpretation of which remains "ticklish".
- Subjects :
- Adult
Aged
Catecholamines metabolism
Female
Humans
Hypothalamo-Hypophyseal System metabolism
Male
Middle Aged
Pituitary-Adrenal System metabolism
Thyroid Gland metabolism
Thyroxine blood
Triiodothyronine blood
Cortisone blood
Depressive Disorder blood
Methoxyhydroxyphenylglycol blood
Thyroid Hormones blood
Thyrotropin blood
Subjects
Details
- Language :
- French
- ISSN :
- 0013-7006
- Volume :
- 17
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- L'Encephale
- Publication Type :
- Academic Journal
- Accession number :
- 1864254