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Direct acylation of aryl bromides with aldehydes by palladium catalysis.
- Source :
-
Journal of the American Chemical Society [J Am Chem Soc] 2008 Aug 13; Vol. 130 (32), pp. 10510-1. Date of Electronic Publication: 2008 Jul 18. - Publication Year :
- 2008
-
Abstract
- A new protocol for the direct acylation of aryl bromides with aldehydes is established. It appears to involve palladium-amine cooperative catalysis, affording synthetically important alkyl aryl ketones in moderate to excellent yields in a straightforward manner, and broadening the scope of metal-catalyzed coupling reactions.
- Subjects :
- Acylation
Catalysis
Aldehydes chemistry
Bromides chemistry
Palladium chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1520-5126
- Volume :
- 130
- Issue :
- 32
- Database :
- MEDLINE
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- 18636731
- Full Text :
- https://doi.org/10.1021/ja804351z