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Gamma knife radiosurgery for intracanalicular acoustic neuromas.
- Source :
-
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia [J Clin Neurosci] 2008 Sep; Vol. 15 (9), pp. 993-7. Date of Electronic Publication: 2008 Jul 09. - Publication Year :
- 2008
-
Abstract
- In the present study we reviewed our long-term experience with radiosurgery for intracanalicular acoustic neuromas. The study involved 25 patients with unilateral intracanalicular acoustic neuromas. The treatment volume was 0.07 to 0.8 cm(3) (median: 0.27 cm(3)). The marginal radiation dose used for treatment was 12 Gy for all patients. The follow-up period ranged from 36 to 132 months (mean: 89 months). The actuarial rate of tumour growth control at 5 and 10 years after radiosurgery was 96%. Hearing preservation was achieved in 16 patients (64%) and improvement (>20 dB relative to presurgical values) was noted in one patient (4%). No patients experienced post-radiosurgery facial palsy or other cranial nerve deficits. Based on our study and long-term follow-up, radiosurgery can produce high rates of tumour growth control and hearing preservation for intracanalicular acoustic neuromas, and is an alternative to surgical resection given its low level of invasiveness. When determining treatment for intracanalicular acoustic neuromas, the condition's benign natural course and the likelihood of hearing preservation must be taken into account.
- Subjects :
- Adult
Aged
Cranial Nerve Neoplasms pathology
Disease Progression
Ear, Inner pathology
Ear, Inner surgery
Female
Hearing Loss, Sensorineural etiology
Hearing Loss, Sensorineural prevention & control
Hearing Loss, Sensorineural surgery
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Neoplasm Recurrence, Local prevention & control
Neuroma, Acoustic pathology
Petrous Bone pathology
Petrous Bone surgery
Postoperative Complications etiology
Postoperative Complications prevention & control
Radiation Dosage
Treatment Outcome
Vestibulocochlear Nerve pathology
Vestibulocochlear Nerve Diseases pathology
Cranial Nerve Neoplasms surgery
Neuroma, Acoustic surgery
Radiosurgery methods
Radiosurgery standards
Vestibulocochlear Nerve surgery
Vestibulocochlear Nerve Diseases surgery
Subjects
Details
- Language :
- English
- ISSN :
- 0967-5868
- Volume :
- 15
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
- Publication Type :
- Academic Journal
- Accession number :
- 18617402
- Full Text :
- https://doi.org/10.1016/j.jocn.2007.09.008