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[Peripheral nerve injury and the degree of motor involvement in Parkinson's disease: a correlation study].

Authors :
Chovancová Z
Kanovský P
Nestrasil I
Dufek J
Nevrlý M
Otruba P
Source :
Casopis lekaru ceskych [Cas Lek Cesk] 2008; Vol. 147 (4), pp. 211-4.
Publication Year :
2008

Abstract

Background: The aim of the study was to validate a hypothesis about the presence of a concomitant peripheral nerves injury in patients suffering from neurodegenerative disorders. The study was focused on the correlation between motor involvement in Parkinson's disease and peripheral nerves injury.<br />Methods and Results: 23 patients suffering from Parkinson's disease, which was diagnosed in terms of strict UK-PDBB criteria, were examined. There were 14 men (mean age: 57 years, mean age at the disease onset: 51 years, mean disease duration: 7 years, mean duration of dopaminergic treatment: 4 years) and 9 women (mean age: 67 years, mean age at the disease onset: 63 years, mean duration of disease: 4 years, mean duration of dopaminergic treatment: 1 year). Polyneuropathy was clinically present and confirmed using EMG examination in 10 patients (43.5 %), 5 men and 5 women.<br />Conclusions: Our observation indicates that the neurodegenerative process can be involved not only in the degeneration of central nervous system, but also in the peripheral disorders in this population.

Details

Language :
Czech
ISSN :
0008-7335
Volume :
147
Issue :
4
Database :
MEDLINE
Journal :
Casopis lekaru ceskych
Publication Type :
Academic Journal
Accession number :
18578374