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Germ cell tumors masquerading as central nervous system sarcoidosis.
- Source :
-
Archives of neurology [Arch Neurol] 1991 May; Vol. 48 (5), pp. 554-6. - Publication Year :
- 1991
-
Abstract
- The diagnosis of central nervous system sarcoidosis is uncertain without typical multisystem involvement. We describe two patients with isolated central nervous system mass lesions whose biopsy results were consistent with sarcoidosis. After a progressive clinical course, they were found to have diencephalic germinomas. Germ cell tumors, in particular, should be considered in the differential diagnosis of central nervous system sarcoidosis as they are potentially treatable, occur in intracranial locations favored by sarcoidosis mass lesions, and may be surrounded by granulomatous inflammation that can be mistaken for the noncaseating granulomas of sarcoidosis.
- Subjects :
- Adolescent
Adult
Biopsy
Brain diagnostic imaging
Brain pathology
Diagnosis, Differential
Humans
Male
Neoplasms, Germ Cell and Embryonal diagnostic imaging
Neoplasms, Germ Cell and Embryonal pathology
Tomography, X-Ray Computed
Brain Diseases diagnosis
Brain Neoplasms diagnosis
Neoplasms, Germ Cell and Embryonal diagnosis
Sarcoidosis diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 0003-9942
- Volume :
- 48
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Archives of neurology
- Publication Type :
- Academic Journal
- Accession number :
- 1850595
- Full Text :
- https://doi.org/10.1001/archneur.1991.00530170118031