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Sex differences in the association between body mass index and total hip or knee joint replacement resulting from osteoarthritis.
- Source :
-
Annals of the rheumatic diseases [Ann Rheum Dis] 2009 Apr; Vol. 68 (4), pp. 536-40. Date of Electronic Publication: 2008 May 26. - Publication Year :
- 2009
-
Abstract
- Objective: To examine the association between body mass index (BMI) and osteoarthritis (OA) leading to total hip (THR) or knee (TKR) joint replacement.<br />Methods: Case-control study design. All patients still living in Iceland who had had a THR or TKR resulting from OA before the end of 2002 were invited to participate. First-degree relatives of participating patients served as controls. A total of 1473 patients (872 women) and 1103 controls (599 women), all born between 1910 and 1939 and who had answered a questionnaire including questions about height and weight, were analysed. A randomly selected sample, representative of the Icelandic population, was used as a secondary control group.<br />Results: The OR, adjusted for age, occupation and presence of hand OA, for having a THR was 1.1 (95% CI 0.9 to 1.5) for overweight men and 1.7 (95% CI 1.0 to 2.9) for obese men. The OR for having a TKR was 1.7 (95% CI 1.1 to 2.6) for overweight men and 5.3 (95% CI 2.8 to 10.1) for obese men. The OR for having a THR was 1.0 (95% CI 0.8 to 1.3) for overweight women and 1.0 (95% CI 0.6 to 1.5) for obese women. The OR for having a TKR was 1.6 (95% CI 1.1 to 2.2) for overweight women and 4.0 (95% CI 2.6 to 6.1) for obese women.<br />Conclusion: This study supports a positive association between high BMI and TKR in both sexes, but for THR the association with BMI seems to be weaker, and possibly negligible for women.
- Subjects :
- Aged
Aged, 80 and over
Arthroplasty, Replacement, Hip
Arthroplasty, Replacement, Knee
Case-Control Studies
Family
Female
Humans
Iceland
Male
Obesity complications
Occupational Diseases surgery
Odds Ratio
Osteoarthritis, Hip surgery
Osteoarthritis, Knee surgery
Overweight complications
Regression Analysis
Risk Assessment methods
Sex Factors
Body Mass Index
Occupational Diseases etiology
Osteoarthritis, Hip etiology
Osteoarthritis, Knee etiology
Subjects
Details
- Language :
- English
- ISSN :
- 1468-2060
- Volume :
- 68
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Annals of the rheumatic diseases
- Publication Type :
- Academic Journal
- Accession number :
- 18504290
- Full Text :
- https://doi.org/10.1136/ard.2007.086868