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Nocardia exalbida brain abscess in a patient with follicular lymphoma.
- Source :
-
International journal of hematology [Int J Hematol] 2008 Jul; Vol. 88 (1), pp. 95-100. Date of Electronic Publication: 2008 May 23. - Publication Year :
- 2008
-
Abstract
- Nocardial brain abscess is a rare but severe complication in patients with malignancy. Nocardia exalbida was isolated in Japan and characterized within the genus Nocardia. We present the first report of N. exalbida brain abscess in a 63-year-old male patient with follicular lymphoma. He developed abnormal neurological findings during follicular lymphoma treatment, brain CT revealed ring-enhancing, multiloculated lesions, and N. exalbida was detected by aspiration of the lesion. He was successfully treated with trimethoprime-sulfamethoxazole (TMP-SMX) and meropenem without craniotomy or repeat aspirations. It should be noted that such an infection can occur in patients treated with conventional chemotherapy against malignant lymphoma.
- Subjects :
- Antineoplastic Combined Chemotherapy Protocols adverse effects
Brain Abscess chemically induced
Brain Abscess microbiology
Brain Abscess pathology
Cyclophosphamide administration & dosage
Cyclophosphamide adverse effects
Doxorubicin administration & dosage
Doxorubicin adverse effects
Humans
Lymphoma, Follicular microbiology
Lymphoma, Follicular pathology
Male
Middle Aged
Nocardia Infections chemically induced
Nocardia Infections pathology
Prednisone administration & dosage
Prednisone adverse effects
Remission Induction
Vincristine administration & dosage
Vincristine adverse effects
Anti-Bacterial Agents administration & dosage
Antineoplastic Combined Chemotherapy Protocols administration & dosage
Brain Abscess drug therapy
Lymphoma, Follicular drug therapy
Nocardia
Nocardia Infections drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 0925-5710
- Volume :
- 88
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- International journal of hematology
- Publication Type :
- Academic Journal
- Accession number :
- 18498026
- Full Text :
- https://doi.org/10.1007/s12185-008-0099-y