Dehydrophenylalanine (DeltaPhe) as a beta breaker: extended structure terminated by a DeltaPhe-induced turn in the pentapeptide Boc-Phe1-Ala2-Ile3-DeltaPhe4-Ala5-OMe.

Subjects

Subjects :

Amino Acid Sequence
Amyloid beta-Peptides chemistry
Amyloid beta-Peptides metabolism
Circular Dichroism
Crystallography, X-Ray
Hydrogen Bonding
Oligopeptides chemical synthesis
Phenylalanine chemistry
Phenylalanine pharmacology
Oligopeptides chemistry
Phenylalanine analogs & derivatives
Protein Structure, Secondary drug effects

Details

Language :

English

ISSN :

1439-7633

Volume :

9

Issue :

9

Database :

MEDLINE

Journal :

Chembiochem : a European journal of chemical biology

Publication Type :

Academic Journal

Accession number :

18478512

Full Text :

https://doi.org/10.1002/cbic.200800053