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Peak mitral annular velocity during early diastole and propagation velocity of early diastolic filling flow are not interchangeable as the parameters of left ventricular early diastolic function.
- Source :
-
The American journal of cardiology [Am J Cardiol] 2008 May 15; Vol. 101 (10), pp. 1467-71. Date of Electronic Publication: 2008 Mar 17. - Publication Year :
- 2008
-
Abstract
- The difference between peak mitral annular velocity during early diastole (Ea) and the propagation velocity of left ventricular (LV) early diastolic filling flow (Vp) obtained using Doppler imaging as LV relaxation parameters was not fully elucidated. Thus, this issue was investigated in 117 patients with suspected coronary artery disease. During cardiac catheterization, LV volumes, the LV relaxation time constant Tp, and inertia force of late systolic aortic flow were obtained. Ea significantly and closely correlated with Tp (r = -0.70, p <0.0001) and significantly but weakly correlated with LV ejection fraction (r = 0.37, p <0.0001) and inertia force (r = 0.34, p = 0.0002). Conversely, Vp significantly and closely correlated with both LV ejection fraction (r = 0.66, p <0.0001) and inertia force (r = 0.72, p <0.0001) and significantly but weakly correlated with Tp (r = - 0.35, p = 0.0001). In conclusion, Ea and Vp reflect different aspects of LV behavior from end-systole to early diastole. Ea can be used to index LV relaxation, whereas Vp might not be a proper parameter of LV intrinsic relaxation because it is significantly dependent on LV systolic function and LV chamber size at end-systole. Both parameters are not interchangeable as those of LV early diastolic function. Vp may be a noninvasive parameter of LV elastic recoil.
- Subjects :
- Cardiac Catheterization methods
Coronary Disease diagnosis
Diastole
Echocardiography, Doppler, Pulsed methods
Female
Follow-Up Studies
Humans
Male
Middle Aged
Mitral Valve diagnostic imaging
Severity of Illness Index
Blood Flow Velocity physiology
Coronary Disease physiopathology
Mitral Valve physiopathology
Myocardial Contraction physiology
Stroke Volume physiology
Ventricular Function, Left physiology
Subjects
Details
- Language :
- English
- ISSN :
- 0002-9149
- Volume :
- 101
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- The American journal of cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 18471459
- Full Text :
- https://doi.org/10.1016/j.amjcard.2008.01.032