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[Experimental basis for possible tumors induction in descendants after placental transmission of chrysotile asbestos fibers].
- Source :
-
Meditsina truda i promyshlennaia ekologiia [Med Tr Prom Ekol] 2008 (3), pp. 33-7. - Publication Year :
- 2008
-
Abstract
- Experiments on white outbred rats helped to establish placental transmission of chrysotile asbestos fibers from mother to fetus with reliable increased incidence of neoplasma in first generation, mainly of respiratory malignancies. Chronic exposure to chrysotile asbestos damaged peripheral lymphocytes and did not affect red bone marrow. Extrapolating the experimental data on placental transmission of chrysotile asbestos to children requires epidemiologic research.
- Subjects :
- Animals
Asbestos, Serpentine toxicity
Asbestosis metabolism
Asbestosis pathology
Disease Models, Animal
Female
Follow-Up Studies
Lung Neoplasms metabolism
Lung Neoplasms pathology
Lymphocytes drug effects
Neoplasms, Experimental
Pregnancy
Rats
Asbestos, Serpentine pharmacokinetics
Asbestosis complications
Lung Neoplasms chemically induced
Placenta metabolism
Subjects
Details
- Language :
- Russian
- ISSN :
- 1026-9428
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Meditsina truda i promyshlennaia ekologiia
- Publication Type :
- Academic Journal
- Accession number :
- 18461800