Overexpression of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase inhibits GM-CSF-dependent colony formation of CD34+ hematopoietic progenitor cells.

Authors :: Hoxha E
Fehse B
Ortmeyer G
Stocking C
Mayr GW
Jücker M
Source :: Leukemia & lymphoma [Leuk Lymphoma] 2008 Jun; Vol. 49 (6), pp. 1206-8.
Publication Year :: 2008

Subjects :: Animals
Antigens, CD34 immunology
Cells, Cultured
Colony-Forming Units Assay
Fetal Blood cytology
Fetal Blood metabolism
Green Fluorescent Proteins genetics
Green Fluorescent Proteins metabolism
Humans
Mice
Mitogen-Activated Protein Kinases metabolism
NIH 3T3 Cells
Phosphorylation
Protein Subunits
Antigens, CD34 metabolism
Granulocyte-Macrophage Colony-Stimulating Factor pharmacology
Hematopoietic Stem Cells physiology
Phosphatidylinositol 3-Kinases metabolism

Full Text Access

Tools