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[Difficulties in the management of localised pulmonary Goodpasture's syndrome].
- Source :
-
Revue des maladies respiratoires [Rev Mal Respir] 2008 Mar; Vol. 25 (3), pp. 323-7. - Publication Year :
- 2008
-
Abstract
- Introduction: The diagnosis of the pulmonary forms of Goodpasture's syndrome is not easy and requires a renal biopsy when no anti-glomerular basement membrane antibodies are detected, since the disease can lead to spontaneous massive intra-alveolar haemorrhage that can be fatal. Treatment for the pulmonary-renal form combining corticosteroids, cyclophosphamide and plasmapheresis should be applied to the pulmonary form to control haemorrhage and prevent relapse.<br />Case Report: We report the case of a patient suffering from the localised pulmonary form of Goodpasture's syndrome in whom the diagnosis was delayed due to a negative indirect immunofluorescent antibody bioassay. After a serious early relapse remission was achieved with comprehensive treatment and a tobacco withdrawal programme.<br />Conclusion: If there is no delay in diagnosis and comprehensive treatment is given, the prognosis for these patients is good with a recovery rate of 80 to 90%.
Details
- Language :
- French
- ISSN :
- 0761-8425
- Volume :
- 25
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Revue des maladies respiratoires
- Publication Type :
- Academic Journal
- Accession number :
- 18449099
- Full Text :
- https://doi.org/10.1016/s0761-8425(08)71552-3