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[Liver cirrhosis: pulmonary function].

Authors :
Marichal I
Dublet P
Medrano G
Hinestrosa H
Tálamo C
Korchoff W
Alvarado R
Quirós E
Source :
G.E.N [G E N] 1991 Oct-Dec; Vol. 45 (4), pp. 263-9.
Publication Year :
1991

Abstract

We performed a functional respiratory examination which consisted of arterial gasometry, spirometry, diffusion capacity to CO2, alveolo-arterial gradient of O2 and pulmonary volumes to 8 patients with cirrhosis diagnosed by clinical history, laboratory exams, abdominal ultrasound and histology. Our results showed a slight obstructive pattern of peripheric airways (FMM: 88.87 +/- 8.7%) in the spirometry, no difference in arterial gases at upright and recumbent position was observed, with low values of apO2 (75.51 +/- 1.16 upright and 75.87 +/- 2.16 mmHg recumbent) without statistic significance. The gradient G(Aa) O2 increased to (30.89 +/- 1.06 mmHg). Besides there was a diffusion abnormality with a DLCO2/VA of (71.87 +/- 6.05%). Breathing 100% O2, did not change the gradient which allows us to postulate the existence of an abnormality of gaseous interchange due to shunts. We found no relationship between albumin levels and DLCO2/VO neither with pO2 in upright position; there was a relationship at recumbent position between the hepatic disorder and the arterial desaturation. We concluded that there is no significant hypoxia even with position changes, there is increase of G (Aa) O2 by shunt type disorders and that this is probably related with albumin levels.

Details

Language :
Spanish; Castilian
ISSN :
0016-3503
Volume :
45
Issue :
4
Database :
MEDLINE
Journal :
G.E.N
Publication Type :
Academic Journal
Accession number :
1843958