Fetal loss after amniocentesis in a series of 5,780 procedures.

Authors :: Gaudry P
Grangé G
Lebbar A
Choiset A
Girard S
Goffinet F
Lewin F
Source :: Fetal diagnosis and therapy [Fetal Diagn Ther] 2008; Vol. 23 (3), pp. 217-21. Date of Electronic Publication: 2008 Feb 20.
Publication Year :: 2008
Abstract: Objectives: Counseling on prenatal diagnosis requires accurate knowledge of the associated risks, including fetal loss. The objective of our study was to assess this risk of amniocentesis in a single center with several operators.<br />Methods: This retrospective analysis concerns only women with singleton pregnancies who underwent amniocentesis between 14(+0) and 23(+6) weeks' gestation.<br />Results: During this 4.5-year period, 5,780 amniocenteses were performed, of which we analyzed 5,319. The rate of fetal loss was 70 in 4,858 tests (1.4%), with a lost-to-follow-up rate of 3.8%.<br />Conclusion: Our results for fetal loss are comparable to those in the largest series with fewer operators already published.<br /> (Copyright 2008 S. Karger AG, Basel.)