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Anxiety and alcoholism: a serotonin link.
- Source :
-
The British journal of psychiatry. Supplement [Br J Psychiatry Suppl] 1991 Sep (12), pp. 34-9. - Publication Year :
- 1991
-
Abstract
- The augmentation of serotonin (5-HT) neurotransmission attenuates alcohol consumption, whereas depletion enhances use. A number of serotonin-specific pharmacological probes appear to be effective in reducing the voluntary consumption of alcohol. The 5-HT1A receptor agonist buspirone is an anxiolytic which has been shown to diminish the desire to consume alcohol in anxious alcoholic patients. Thus, serotonin may represent a common denominator for a spectrum of behavioural disorders including anxiety and alcoholism. Novel serotonin drugs, such as the azapirones, may usefully supplement conventional treatment strategies for substance abuse.
- Subjects :
- Alcoholism psychology
Alcoholism rehabilitation
Animals
Anxiety Disorders psychology
Anxiety Disorders rehabilitation
Brain drug effects
Brain physiopathology
Buspirone therapeutic use
Disease Models, Animal
Humans
Personality Inventory
Receptors, Serotonin drug effects
Receptors, Serotonin physiology
Selective Serotonin Reuptake Inhibitors therapeutic use
Alcoholism physiopathology
Anxiety Disorders physiopathology
Serotonin physiology
Subjects
Details
- Language :
- English
- ISSN :
- 0960-5371
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- The British journal of psychiatry. Supplement
- Publication Type :
- Academic Journal
- Accession number :
- 1840761