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Oxidative stress parameters in hemodialysis patients with or without diabetes.
- Source :
-
Romanian journal of internal medicine = Revue roumaine de medecine interne [Rom J Intern Med] 2006; Vol. 44 (4), pp. 433-42. - Publication Year :
- 2006
-
Abstract
- Oxidative stress (imbalance of antioxidant and prooxidants in favour of the later) is considered to be a feature of diabetes and chronic renal failure. Carbonyl stress defined as accumulation of reactive carbonyl compounds due to excess production or disturbed clearance from the body is thought to amplify oxidative stress in these conditions. The accumulation of carbonyl compounds can be also a consequence of oxidative stress. A vicious cycle can thus be formed. We have studied the association between carbonyl stress markers (dicarbonyl compounds, Amadori products) and oxidative stress markers (total plasmatic thiols and malondialdehyde level) in hemodialysed patients with or without diabetes taking into account the levels of possible excess substrates (glucose and triglycerides). We have concluded that hemodialysed diabetes patients are more susceptible to oxidative stress than hemodialysed patients without diabetes.
- Subjects :
- Case-Control Studies
Glycation End Products, Advanced metabolism
Humans
Sulfhydryl Compounds blood
Thiobarbituric Acid Reactive Substances metabolism
Uremia therapy
Diabetes Mellitus, Type 2 complications
Diabetes Mellitus, Type 2 metabolism
Oxidative Stress physiology
Renal Dialysis
Uremia complications
Uremia metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1220-4749
- Volume :
- 44
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Romanian journal of internal medicine = Revue roumaine de medecine interne
- Publication Type :
- Academic Journal
- Accession number :
- 18386620