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Recurrent orbital inflammation and Whipple disease.
- Source :
-
Ocular immunology and inflammation [Ocul Immunol Inflamm] 2008 Jan-Feb; Vol. 16 (1), pp. 37-9. - Publication Year :
- 2008
-
Abstract
- Purpose: To describe a recurrent case of idiopathic orbital inflammation (OI) associated with Whipple disease.<br />Methods: Observational case report.<br />Results: A 63-year-old woman developed myositis or idiopathic orbital inflammation (OI). Whipple disease had been diagnosed 1 year before by duodenal biopsy. OI appeared 1 year following the end of a long course of trimethoprim-sulfamethoxazole treatment. During follow-up months later, recurrent OI was noted in the same and contralateral orbits. Flare-ups of OI were suggestive of disease relapse and subsequent duodenal biopsy confirmed the presence of PAS-positive particles in macrophages. Treatment with trimethoprim-sulfamethoxazole and corticosteroids was necessary to prevent recurrences.<br />Conclusions: Recurrence of duodenal Whipple disease may be associated with an OI picture that is immmunologically mediated.
- Subjects :
- Adrenal Cortex Hormones therapeutic use
Anti-Infective Agents therapeutic use
Drug Therapy, Combination
Duodenum
Female
Humans
Inflammation diagnosis
Inflammation drug therapy
Inflammation etiology
Inflammation pathology
Middle Aged
Orbital Diseases diagnosis
Orbital Diseases drug therapy
Orbital Diseases pathology
Secondary Prevention
Tomography, X-Ray Computed
Trimethoprim, Sulfamethoxazole Drug Combination therapeutic use
Whipple Disease drug therapy
Orbital Diseases etiology
Whipple Disease complications
Subjects
Details
- Language :
- English
- ISSN :
- 1744-5078
- Volume :
- 16
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Ocular immunology and inflammation
- Publication Type :
- Academic Journal
- Accession number :
- 18379941
- Full Text :
- https://doi.org/10.1080/09273940801899756