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Targeting glycoproteins or glycolipids and their metabolic pathways for antiparasite therapy.

Authors :
Bandyopadhyay SM
Mandal C
Source :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2008; Vol. 625, pp. 87-102.
Publication Year :
2008

Abstract

Carbohydrate-based therapy, known as glycotherapeutics, is a new and emerging field that promises to be the future hope for combating kinetoplastid infections more efficiently and effectively. Targeting novel glycoproteins/lipids, which are important disease determinants of kinetoplastid diseases, have helped in the development of this field. Better and refined understanding of all the available data would possibly help us in providing a future direction for rational drug design and better disease management. This review intends to focus on such lines, which will give us an insight into the future hope for development of novel therapeutic strategies through glycobiological platform for combating kinetoplastid infections.

Details

Language :
English
ISSN :
0065-2598
Volume :
625
Database :
MEDLINE
Journal :
Advances in experimental medicine and biology
Publication Type :
Academic Journal
Accession number :
18365661
Full Text :
https://doi.org/10.1007/978-0-387-77570-8_8