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Targeting glycoproteins or glycolipids and their metabolic pathways for antiparasite therapy.
- Source :
-
Advances in experimental medicine and biology [Adv Exp Med Biol] 2008; Vol. 625, pp. 87-102. - Publication Year :
- 2008
-
Abstract
- Carbohydrate-based therapy, known as glycotherapeutics, is a new and emerging field that promises to be the future hope for combating kinetoplastid infections more efficiently and effectively. Targeting novel glycoproteins/lipids, which are important disease determinants of kinetoplastid diseases, have helped in the development of this field. Better and refined understanding of all the available data would possibly help us in providing a future direction for rational drug design and better disease management. This review intends to focus on such lines, which will give us an insight into the future hope for development of novel therapeutic strategies through glycobiological platform for combating kinetoplastid infections.
- Subjects :
- Animals
Glycoconjugates metabolism
Glycoconjugates physiology
Glycolipids physiology
Glycoproteins drug effects
Glycoproteins physiology
Humans
Protozoan Infections metabolism
Protozoan Infections parasitology
Protozoan Proteins drug effects
Protozoan Proteins physiology
Trypanosomatina metabolism
Glycolipids metabolism
Glycoproteins metabolism
Protozoan Infections drug therapy
Protozoan Proteins metabolism
Trypanocidal Agents pharmacology
Trypanosomatina drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 0065-2598
- Volume :
- 625
- Database :
- MEDLINE
- Journal :
- Advances in experimental medicine and biology
- Publication Type :
- Academic Journal
- Accession number :
- 18365661
- Full Text :
- https://doi.org/10.1007/978-0-387-77570-8_8