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[Reversible posterior leukoencephalopathy: report of two cases after vincristine treatment].

Authors :
Hualde Olascoaga J
Molins Castiella T
Souto Hernández S
Becerril Moreno F
Yoldi Petri ME
Sagaseta de Ilurdoz M
Molina Garicano J
Source :
Anales de pediatria (Barcelona, Spain : 2003) [An Pediatr (Barc)] 2008 Mar; Vol. 68 (3), pp. 282-5.
Publication Year :
2008

Abstract

Reversible posterior leukoencephalopathy syndrome is a clinical-radiological phenomenon associated with headache, vomiting, lethargy, visual disturbances and seizures, concomitant with radiological abnormalities predominantly within posterior cerebral white matter due to cerebral edema. There are multiple triggers as acute hypertension, cancer, hematological disease, renal pathology, red cells transfusions and different drugs. We present two patients with reversible posterior leukoencephalopathy under treatment for acute lymphoblastic leukemia because of the probable association with vinca alkaloids.

Details

Language :
Spanish; Castilian
ISSN :
1695-4033
Volume :
68
Issue :
3
Database :
MEDLINE
Journal :
Anales de pediatria (Barcelona, Spain : 2003)
Publication Type :
Academic Journal
Accession number :
18358142
Full Text :
https://doi.org/10.1157/13116711