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[Optimal extraction of Dingxiang jiangqi granules].
- Source :
-
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2007 Nov; Vol. 32 (21), pp. 2252-5. - Publication Year :
- 2007
-
Abstract
- Objective: To screen and optimize the extraction of Dingxiangjiangqi granules.<br />Method: The extraction route was screened by using pharmacodynamic experiment and the extraction conditions were optimized by orthogonal design and taking extract yield, content of naringin and tetrahydropalmatine as indexes.<br />Result: The pharmacodynamic result showed that aqueous extract had the best effect to cure the esophagitis of rats and the optimized extraction technique was adding 12 times water, extracting 0. 5 hour for 3 times.<br />Conclusion: The optimum extraction was simple, reasonable, stable and useful for further development.
- Subjects :
- Animals
Berberine Alkaloids analysis
Drug Combinations
Drugs, Chinese Herbal chemistry
Drugs, Chinese Herbal pharmacology
Esophagitis, Peptic drug therapy
Esophagitis, Peptic pathology
Esophagus drug effects
Esophagus pathology
Flavanones analysis
Male
Phytotherapy
Random Allocation
Rats
Rats, Sprague-Dawley
Technology, Pharmaceutical methods
Drugs, Chinese Herbal isolation & purification
Plants, Medicinal chemistry
Syzygium chemistry
Subjects
Details
- Language :
- Chinese
- ISSN :
- 1001-5302
- Volume :
- 32
- Issue :
- 21
- Database :
- MEDLINE
- Journal :
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Publication Type :
- Academic Journal
- Accession number :
- 18309666