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[Primary hyperparathyroidism: current role of bone densitometry].

Authors :
Alcaraz MJ
Lorente R
Del Valle Y
Godoy H
Gómez J
Source :
Radiologia [Radiologia] 2008 Jan-Feb; Vol. 50 (1), pp. 37-45.
Publication Year :
2008

Abstract

Objective: To describe the usefulness of bone densitometry in the diagnosis and follow-up of patients with primary hyperthyroidism (PHPT).<br />Material and Methods: Retrospective review of 48 patients with PHPT; 27 received surgical treatment and 21 medical treatment. Radiologic and biochemical findings and bone mass were evaluated at the start of the study and after one and two years.<br />Results: All patients had elevated PTH levels and 87% had normal or moderately increased calcemia. The most common clinical presentations were renal colic (34%) and the absence of symptoms (22.8%). The sensitivity of scintigraphy was 75% and the sensitivity of ultrasonography was 12%. We found osteopenia in 70.3% of patients and osteoporosis in 81.3%, fundamentally in the radius and spine. Bone mass at one year and at two years remained similar in the femur (73.8%) and spine (81.8%) in 58% and 50% of the patients, respectively. Increased bone mass was seen in the femur (30.4%) in 13.6% of the patients and in the spine (33.3%) in 50% of the patients. This increase was greater in the group that received surgical treatment. Calcemia and PTH were decreased by 69.2% and 76.9 %, respectively, in the patients that underwent surgery. In the group that received medical treatment, calcemia remained similar and PTH was decreased by 50%. Fractures developed in 21.8% of the patients.<br />Conclusions: Densitometry assesses the repercussions of the disease on bone mass at the start of treatment and after treatment. Osteoporosis is a common finding. Gains in bone mass occurred fundamentally in patients that had undergone surgery. Bone mass remained similar in a high percentage of patients in both groups.

Details

Language :
Spanish; Castilian
ISSN :
0033-8338
Volume :
50
Issue :
1
Database :
MEDLINE
Journal :
Radiologia
Publication Type :
Academic Journal
Accession number :
18275787
Full Text :
https://doi.org/10.1016/s0033-8338(08)71927-1