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[Diagnostics of Lyme disease].
- Source :
-
Medycyna pracy [Med Pr] 2007; Vol. 58 (5), pp. 439-47. - Publication Year :
- 2007
-
Abstract
- Although many years have passed since Borrelia burgdorferi was first identified, advances in understanding biology and clinical course of infection made and new diagnostic procedures developed, Lyme disease is still difficult to diagnose. Therefore, it is often wrongly diagnosed and unnecessarily treated. In this paper we analyzed the latest data on Lyme disease diagnostic methods, paying much attention to their limitations and correct interpretation of results. In routine diagnosis of this diseases, indirect tests, based on the detection of specific IgM and IgG antibodies, are most useful. The Lyme disease diagnosis should begin with screening tests, which are highly sensitive but not specific enough and sometimes yield false positive results, then all positive results should be verified by confirmation tests, which allow to distinguish between true positive results and healthy individuals with false positive ones.
- Subjects :
- Enzyme-Linked Immunosorbent Assay
Fluorescent Antibody Technique
Hemagglutination Tests
Humans
Immunoglobulin G blood
Immunoglobulin M blood
Sensitivity and Specificity
Agricultural Workers' Diseases diagnosis
Antibodies, Bacterial blood
Borrelia burgdorferi isolation & purification
Lyme Neuroborreliosis diagnosis
Subjects
Details
- Language :
- Polish
- ISSN :
- 0465-5893
- Volume :
- 58
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Medycyna pracy
- Publication Type :
- Academic Journal
- Accession number :
- 18274096