Back to Search
Start Over
TrpY regulation of trpB2 transcription in Methanothermobacter thermautotrophicus.
- Source :
-
Journal of bacteriology [J Bacteriol] 2008 Apr; Vol. 190 (7), pp. 2637-41. Date of Electronic Publication: 2008 Feb 08. - Publication Year :
- 2008
-
Abstract
- TrpY binds specifically to TRP box sequences upstream of trpB2, but the repression of trpB2 transcription requires additional TrpY assembly that is stimulated by but not dependent on the presence of tryptophan. Inhibitory complex formation is prevented by insertions within the regulatory region and by a G149R substitution in TrpY, even though TrpY(G149R) retains both TRP box DNA- and tryptophan-binding abilities.
- Subjects :
- Archaeal Proteins metabolism
Archaeal Proteins physiology
Base Sequence
DNA Footprinting
Electrophoretic Mobility Shift Assay
Gene Expression Regulation, Archaeal
Methanobacteriaceae metabolism
Molecular Sequence Data
Promoter Regions, Genetic genetics
Protein Binding
Repressor Proteins metabolism
Repressor Proteins physiology
Tryptophan metabolism
Tryptophan Synthase metabolism
Tryptophan Synthase physiology
Archaeal Proteins genetics
Methanobacteriaceae genetics
Repressor Proteins genetics
Transcription, Genetic
Tryptophan Synthase genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1098-5530
- Volume :
- 190
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Journal of bacteriology
- Publication Type :
- Academic Journal
- Accession number :
- 18263726
- Full Text :
- https://doi.org/10.1128/JB.01926-07