Back to Search
Start Over
Comparative therapeutic effect of toltrazuril, sulphadimidine and amprolium on Eimeria bovis and Eimeria zuernii given at different times following infection in buffalo calves (Bubalus bubalis).
- Source :
-
Preventive veterinary medicine [Prev Vet Med] 2008 Apr 17; Vol. 84 (1-2), pp. 161-70. Date of Electronic Publication: 2008 Feb 11. - Publication Year :
- 2008
-
Abstract
- We compared the therapeutic effect of three anticoccidial drugs (toltrazuril, sulphadimidine and amprolium) in buffalo (Bubalus bubalis) calves experimentally infected with Eimeria bovis (E. bovis) and E. zuernii oocysts (3 x 104oocyst/calf). Buffalo calves (1.5-4 month old, 70-kg body weight) were randomly allocated into 3 groups (9 calves each). Group T was experimentally infected with oocysts and treated with toltrazuril (20 mg/kg BW twice orally at a 1-week interval). Group S was experimentally infected with oocysts and treated with sulphadimidine (125 mg/kg injected IM followed by half dose for 4 successive days). Group A was experimentally infected with oocysts and treated with amprolium (50 mg/kg orally for 7 successive days). Each group had three subgroups (three calves/subgroup) to represent timing of the drug administration: 1st day of coccidia infection (FD), onset of clinical signs of coccidiosis (CC), and onset of oocyst shedding into the faeces (OS). Clinical signs, body-weight gain (BWG) and number of oocysts per gram feces (OPG) were monitored daily for 35 days post-infection (DPI). The OPG were reduced (but the BWG was not different) in the T calves compared to S and A calves. Within the same group, treatment from the 1st day of infection reduced the OPG and increased the BWG compared to the later treatment timings.
- Subjects :
- Amprolium administration & dosage
Animals
Coccidiosis drug therapy
Coccidiostats administration & dosage
Coccidiostats therapeutic use
Drug Administration Schedule
Feces parasitology
Sulfanilamides administration & dosage
Triazines administration & dosage
Weight Gain
Amprolium therapeutic use
Buffaloes parasitology
Coccidiosis veterinary
Eimeria drug effects
Sulfanilamides therapeutic use
Triazines therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 0167-5877
- Volume :
- 84
- Issue :
- 1-2
- Database :
- MEDLINE
- Journal :
- Preventive veterinary medicine
- Publication Type :
- Academic Journal
- Accession number :
- 18262668
- Full Text :
- https://doi.org/10.1016/j.prevetmed.2007.12.013