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Lymphoepithelioma-like carcinoma of the breast: not Epstein-Barr virus-, but human papilloma virus-positive.
- Source :
-
Human pathology [Hum Pathol] 2008 Feb; Vol. 39 (2), pp. 298-301. - Publication Year :
- 2008
-
Abstract
- Lymphoepithelioma-like carcinoma of the breast is a rare tumor, with fewer than 20 cases documented in the literature. None of the published cases was Epstein-Barr virus positive, and our case was also Epstein-Barr virus negative. However, in our case, human papilloma virus (HPV) types 18 and 33 DNA could be demonstrated within the tumor tissue. Many years previously, the patient underwent hysterectomy for cervical carcinoma in situ which showed the presence of HPV-33. To the best of our knowledge, this is the first report on lymphoepithelioma-like carcinoma of the breast where high-risk HPV infection may be suggested as an etiological factor in a patient with a previous history of cervical carcinoma in situ.
- Subjects :
- Adult
Breast Neoplasms pathology
Breast Neoplasms surgery
Carcinoma pathology
Carcinoma surgery
Cell Nucleus pathology
Cell Nucleus virology
DNA, Neoplasm analysis
DNA, Viral analysis
Female
Genes, Viral genetics
Herpesvirus 4, Human genetics
Herpesvirus 4, Human isolation & purification
Human papillomavirus 18 genetics
Humans
Papillomavirus Infections pathology
Papillomavirus Infections surgery
Breast Neoplasms virology
Carcinoma virology
Human papillomavirus 18 isolation & purification
Papillomavirus Infections virology
Subjects
Details
- Language :
- English
- ISSN :
- 0046-8177
- Volume :
- 39
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Human pathology
- Publication Type :
- Academic Journal
- Accession number :
- 18206498
- Full Text :
- https://doi.org/10.1016/j.humpath.2007.08.006