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[Morphologic observation of the regenerated nerve in reconstructed penis with sensory nerve implantation in rabbit].
- Source :
-
Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery [Zhonghua Zheng Xing Wai Ke Za Zhi] 2007 Sep; Vol. 23 (5), pp. 416-9. - Publication Year :
- 2007
-
Abstract
- Objective: To investigate the mechanism of sensory nerve regeneration of the reconstructed penis with sensory nerve implantation and to explore a new surgical technique to improve the postoperative sensory function in phallic reconstruction.<br />Methods: Adult male New Zealand rabbits were randomly divided into experimental group (n = 20, with sensory nerve implantation) and control group (n = 20, without sensory nerve implantation), which were both performed phalloplasty with a superficial epigastric faciovascular pedicle flap. Postoperatively, the nerve regeneration process of the reconstructed penis was observed histologically.<br />Results: In experimental group, the amount of CGRP positive nerve fibers increased markedly with the time prolonged, whereas merely a few CGRP positive fibers scattered in deep dermis 6 months later in the other group. The cutaneous sensory nerve regeneration of the reconstructed penis in experimental group shows the procedure that the myelinated axon began to exist within 3 months, thereafter the myelinated axon and unmyelinated axon were both observed under the electron microscope.<br />Conclusion: These findings show that the rabbit model of phalloplasty with sensory nerve implantation can acquire well sensory reinnervation, and bring a light to clinical application for restoration of sensory function in reconstructed penis.
Details
- Language :
- Chinese
- ISSN :
- 1009-4598
- Volume :
- 23
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery
- Publication Type :
- Academic Journal
- Accession number :
- 18161359