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Synthesis and antiaggregatory activity of antiflammin related peptides.

Authors :
Marastoni M
Scaranari V
Salvadori S
Tomatis R
Spisani S
Traniello S
Source :
Farmaco (Societa chimica italiana : 1989) [Farmaco] 1991 Nov; Vol. 46 (11), pp. 1265-72.
Publication Year :
1991

Abstract

The peptide H-Lys-Val-Leu-Asp-OH (KVLD), derived from antiflammins, and its analog H-Lys-Val-Asp-Leu-OH (KVDL) were prepared by solution synthesis. KVLD does not inhibit platelet aggregation in contrast to the results recently published.

Subjects

Subjects :
Amino Acid Sequence
Chemical Phenomena
Chemistry, Physical
Fibrinogen metabolism
Humans
In Vitro Techniques
Molecular Sequence Data
Oligopeptides pharmacology
Platelet Aggregation Inhibitors pharmacology
Oligopeptides chemical synthesis
Platelet Aggregation Inhibitors chemical synthesis

Details

Language :
English
ISSN :
0014-827X
Volume :
46
Issue :
11
Database :
MEDLINE
Journal :
Farmaco (Societa chimica italiana : 1989)
Publication Type :
Academic Journal
Accession number :
1811615

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