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Accuracy of endoscopic ultrasound in the diagnosis of distal and celiac axis lymph node metastasis in esophageal cancer: a meta-analysis and systematic review.
- Source :
-
Digestive diseases and sciences [Dig Dis Sci] 2008 Sep; Vol. 53 (9), pp. 2405-14. Date of Electronic Publication: 2007 Dec 20. - Publication Year :
- 2008
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Abstract
- Background: Published data on the accuracy of endoscopic ultrasound (EUS) for staging distant and celiac axis lymph node (CLN) metastasis in patients with esophageal cancer (ECA) has varied.<br />Aim: To evaluate the accuracy of EUS in diagnosing distal and CLN metastasis in ECA patients.<br />Study Selection: EUS studies confirmed by surgery were selected.<br />Statistical Method: Pooling was conducted by both fixed and random-effects models.<br />Results: Data were extracted from 25 studies (N = 2029) which met the inclusion criteria. In ECA patients, pooled sensitivity of EUS was 67.2% (95% CI: 62.6-71.6) in diagnosis of distal metastasis and 66.6% (95% CI: 61.9-71.1) in diagnosis of CLN metastasis. EUS had a pooled specificity of 97.9% (95% CI: 97.1-98.6) for distal metastasis and 98.1% (95% CI: 97.3-98.7) for CLN metastasis.<br />Conclusions: Although EUS has excellent specificity in accurately diagnosing distal and CLN metastasis in patients with ECA, the sensitivity is low.
Details
- Language :
- English
- ISSN :
- 0163-2116
- Volume :
- 53
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Digestive diseases and sciences
- Publication Type :
- Academic Journal
- Accession number :
- 18097752
- Full Text :
- https://doi.org/10.1007/s10620-007-0152-3