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Clinical evaluation of sodium hyaluronate in the treatment of patients with sopraspinatus tendinosis under echographic guide: experimental study of periarticular injections.
Clinical evaluation of sodium hyaluronate in the treatment of patients with sopraspinatus tendinosis under echographic guide: experimental study of periarticular injections.
- Source :
-
European journal of radiology [Eur J Radiol] 2008 Oct; Vol. 68 (1), pp. 170-3. Date of Electronic Publication: 2007 Dec 21. - Publication Year :
- 2008
-
Abstract
- Purpose: The purpose of this study was to examine the effect of periarticular injection of hyaluronate into shoulders with supraspinatus tendinosis under echographic guide.<br />Methods and Materials: The subjects were 56 patients with clinical, echographic and magnetic resonance diagnosis of supraspinatus tendinosis. They were divided in two groups by random sampling; 28 patients were assigned in SH group (sodium hyaluronate) and 28 patients in SC group (sodium chloride). The test drug was 20mg sodium hyaluronate (2ml, Hyalgan, Fidia SpA, Abano T., P.M. 500-700.000, 20mg/2ml).<br />Results: Preliminary results showed that sodium hyaluronate presented the highest efficacy in the improvement of clinical symptoms and recovery of functional status in patients with supraspinatus tendinosis in fact the mean V.A.S. score (Visual Analogue Scale) at 1 month after the end of the infiltrative cycle was 8.0 in the SC group vs. 2.8 in SH group and these numerical data were substantially unchanged also after 3 and 4 months.<br />Conclusion: Hyaluronate injection under echographic guide should be use not only as a lubricant but also to prevent articular cartilage degeneration and cover and protect the articular cartilage; indeed sodium hyaluronate can decrease inflammatory joint process.
- Subjects :
- Adjuvants, Immunologic administration & dosage
Adult
Aged
Female
Humans
Injections, Intra-Articular
Male
Middle Aged
Shoulder Joint drug effects
Treatment Outcome
Hyaluronic Acid administration & dosage
Shoulder Joint diagnostic imaging
Tendinopathy diagnostic imaging
Tendinopathy drug therapy
Ultrasonography, Interventional methods
Subjects
Details
- Language :
- English
- ISSN :
- 0720-048X
- Volume :
- 68
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- European journal of radiology
- Publication Type :
- Academic Journal
- Accession number :
- 18096343
- Full Text :
- https://doi.org/10.1016/j.ejrad.2007.11.001