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Sensitivity of an Acinetobacter baylyi mpl mutant to DNA damage.

Authors :
Chakravorty A
Klovstad M
Peterson G
Lindeman RE
Gregg-Jolly LA
Source :
Applied and environmental microbiology [Appl Environ Microbiol] 2008 Feb; Vol. 74 (4), pp. 1273-5. Date of Electronic Publication: 2007 Dec 14.
Publication Year :
2008

Abstract

A mutant derived from Acinetobacter baylyi ADP1 was isolated from a screen for genes involved in the response to DNA damage. This derivative has an insertion in the mpl gene which encodes a peptidoglycan-recycling protein. We demonstrate that the insertion renders cells sensitive to mitomycin C and to UV.

Subjects

Subjects :
Acinetobacter drug effects
Acinetobacter radiation effects
Mitomycin toxicity
Ultraviolet Rays
Acinetobacter genetics
DNA Damage
Metalloendopeptidases genetics
Mutation genetics

Details

Language :
English
ISSN :
1098-5336
Volume :
74
Issue :
4
Database :
MEDLINE
Journal :
Applied and environmental microbiology
Publication Type :
Academic Journal
Accession number :
18083886
Full Text :
https://doi.org/10.1128/AEM.02347-07
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