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Screening for bipolar disorder: the utility and comparative properties of the MSS and MDQ measures.
- Source :
-
Journal of affective disorders [J Affect Disord] 2008 Jul; Vol. 109 (1-2), pp. 83-9. Date of Electronic Publication: 2008 Feb 20. - Publication Year :
- 2008
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Abstract
- Background: Our objective was to further determine the diagnostic utility of the Mood Swings Survey (MSS) in distinguishing bipolar and unipolar disorders, and draw comparisons between this measure and the widely-used Mood Disorder Questionnaire (MDQ).<br />Methods: A total of 247 consecutively recruited patients attending the Black Dog Institute Depression Clinic were administered the Mood Swings Survey (MSS) as part of a computerized Mood Assessment Program (MAP), in addition to undergoing clinical assessment by two independent psychiatrists. The MDQ, along with a structured interview assessing DSM-IV criteria for bipolar disorder, was administered to a sub-sample of patients.<br />Results: The MSS-46 demonstrates comparable sensitivity and specificity to the MDQ (86.5% and 60.0% vs. 78.8% and 71.4%) when using pre-established cut-off scores. MSS diagnoses embedded within the computerized program correctly classified 82.2% of cases when compared to clinician diagnosis. Optimal cut-off scores derived in the current sample were > or = 35 (Se=88.5%, Sp=60.0%) for the MSS-46, and > or = 7 (Se=78.8%, Sp=71.4%) for the MDQ, indicating acceptable stability of cut-off scores in differing samples for both measures.<br />Limitations: ROC analyses compromised 'true' estimates of MSS sensitivity and specificity as a number of patients who did not affirm the initial screener question were excluded from these analyses.<br />Conclusions: Further work is required to evaluate the diagnostic utility of the MSS in differing clinical and community samples to determine the stability of its cut-off score and to refine the item set.
Details
- Language :
- English
- ISSN :
- 0165-0327
- Volume :
- 109
- Issue :
- 1-2
- Database :
- MEDLINE
- Journal :
- Journal of affective disorders
- Publication Type :
- Academic Journal
- Accession number :
- 18082895
- Full Text :
- https://doi.org/10.1016/j.jad.2007.11.003