Back to Search
Start Over
Pyrene-functionalized 2'-amino-alpha-L-LNA as potential diagnostic probes.
- Source :
-
Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2007; Vol. 26 (10-12), pp. 1407-9. - Publication Year :
- 2007
-
Abstract
- Oligodeoxyribonucleotides (ONs) containing two incorporations of 2'-N-(pyren-1-yl)acetyl-2'-amino-alpha-L-LNA monomer Y are sensitive probes for detection of single nucleotide polymorphisms (SNP) in DNA. In addition, the ability of ONs containing pyrene-functionalized 2'-amino-alpha-L-LNA monomers (W-Z) to stabilize duplexes with an abasic site is demonstrated.
Details
- Language :
- English
- ISSN :
- 1525-7770
- Volume :
- 26
- Issue :
- 10-12
- Database :
- MEDLINE
- Journal :
- Nucleosides, nucleotides & nucleic acids
- Publication Type :
- Academic Journal
- Accession number :
- 18066793
- Full Text :
- https://doi.org/10.1080/15257770701538908