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Ultrastructural changes of crop-sac and lactotrophs after systemic or intraventricular administration of drugs enhancing cholinergic transmission in pigeons.
- Source :
-
Anatomischer Anzeiger [Anat Anz] 1991; Vol. 173 (4), pp. 199-208. - Publication Year :
- 1991
-
Abstract
- The ultrastructural effects of drugs enhancing, by different mechanisms, cholinergic transmission in the crop-sac (the target for prolactin secretion in birds) and the anterior pituitary lactotrophs, were studied in pigeons (Columba livia). The systemic or intraventricular administration of physostigmine, carbachol and muscarine produced maximal crop-sac stimulation with milk-like secretion, as demonstrated by the observation of ultrastructural changes in the lactiferous areas through scanning and transmission electron microscopy of the crop-sac mucosa. A marked activation was also observed in anterior pituitary lactotrophs. Crop-sac and anterior pituitary lactotrophs stimulatory effects were prevented by an atropine pretreatment, but not by mecamylamine and pempidine pretreatments. The present results suggest that muscarinic receptors at the hypothalamic and/or anterior pituitary level are involved in avian species in the control of prolactin secretion.
- Subjects :
- Animals
Atropine administration & dosage
Atropine pharmacology
Carbachol administration & dosage
Carbachol pharmacology
Columbidae anatomy & histology
Crop, Avian metabolism
Crop, Avian ultrastructure
Endoplasmic Reticulum drug effects
Endoplasmic Reticulum ultrastructure
Female
Golgi Apparatus drug effects
Golgi Apparatus ultrastructure
Infusions, Parenteral veterinary
Injections, Intraventricular veterinary
Mecamylamine administration & dosage
Mecamylamine pharmacology
Microscopy, Electron
Microscopy, Electron, Scanning
Mucous Membrane drug effects
Mucous Membrane metabolism
Mucous Membrane ultrastructure
Muscarine administration & dosage
Muscarine pharmacology
Pempidine administration & dosage
Pempidine pharmacology
Physostigmine administration & dosage
Physostigmine pharmacology
Pituitary Gland, Anterior metabolism
Pituitary Gland, Anterior ultrastructure
Columbidae metabolism
Crop, Avian drug effects
Parasympathomimetics pharmacology
Pituitary Gland, Anterior drug effects
Prolactin metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 0003-2786
- Volume :
- 173
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Anatomischer Anzeiger
- Publication Type :
- Academic Journal
- Accession number :
- 1803944