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Cutaneous granulomas in children with combined immunodeficiency.
- Source :
-
Journal of the American Academy of Dermatology [J Am Acad Dermatol] 1991 Nov; Vol. 25 (5 Pt 1), pp. 761-6. - Publication Year :
- 1991
-
Abstract
- Noninfectious cutaneous granulomas, particularly in an acral distribution, may be an early sign of mixed cellular and humoral immunodeficiency. Special stains of skin biopsy sections and cultures for bacteria, acid-fast bacilli, and fungi are important in eliminating the possibility of underlying pathogens. In three children with combined immunodeficiency and cutaneous granulomas, the administration of moderate- to high-dose systemic corticosteroids was the most effective therapy. However, careful consideration should be given before administering systemic corticosteroids to an immunocompromised patient.
Details
- Language :
- English
- ISSN :
- 0190-9622
- Volume :
- 25
- Issue :
- 5 Pt 1
- Database :
- MEDLINE
- Journal :
- Journal of the American Academy of Dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 1802897
- Full Text :
- https://doi.org/10.1016/s0190-9622(08)80965-6