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[Clinical risk-adapted therapies in systemic sclerosis].
- Source :
-
Zeitschrift fur Rheumatologie [Z Rheumatol] 2007 Dec; Vol. 66 (8), pp. 672-4, 676-8. - Publication Year :
- 2007
-
Abstract
- Systemic sclerosis is a challenging disease in terms of early risk assessment and the implications for therapy. The current article draws on a literature analysis and on personal experience of over 450 patients with systemic sclerosis and related illnesses, describing an attempt at a risk-adapted treatment strategy for patients with systemic sclerosis, and is intended to be used as a discussion paper. A major point of emphasis is on novel therapeutic options for patients who are refractory to current treatment strategies and who are at a high risk of serious complications or a limited prognosis. The paper also highlights possible future treatment options, including vasoactive, cellular and immune suppressant treatments.
- Subjects :
- Antibodies, Monoclonal therapeutic use
B-Lymphocytes drug effects
Cell Division drug effects
Combined Modality Therapy
Humans
Immunosuppressive Agents adverse effects
Immunosuppressive Agents therapeutic use
Organ Transplantation
Prognosis
Risk Assessment
Scleroderma, Systemic complications
Scleroderma, Systemic diagnosis
Stem Cell Transplantation
T-Lymphocytes drug effects
Tumor Necrosis Factor-alpha antagonists & inhibitors
Vasodilator Agents adverse effects
Vasodilator Agents therapeutic use
Scleroderma, Systemic therapy
Subjects
Details
- Language :
- German
- ISSN :
- 0340-1855
- Volume :
- 66
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Zeitschrift fur Rheumatologie
- Publication Type :
- Academic Journal
- Accession number :
- 17994243
- Full Text :
- https://doi.org/10.1007/s00393-007-0225-x