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[Expressions of NF-kappaB p65 in laryngeal carcinoma and normal mucous membrane and its clinical significance].

Authors :
Zhang L
Jing Y
Yu L
Source :
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery [Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi] 2007 Aug; Vol. 21 (15), pp. 692-4.
Publication Year :
2007

Abstract

Objective: To evaluate expressions of NF-kappaB p65 in laryngeal carcinoma and normal mucous membrane and its clinical significance.<br />Method: The immunohistochemical method and the in situ hybridization were employed in detecting the NF-kappaB p65 expressions in surgical specimen from 48 laryngeal carcinoma and 20 normal mucous membrane.<br />Result: (1) The expression of NF kappaB p65 was higher than in normal laryngeal mucous membrane. (2) Positive expression of NF-kappaB p65 correlated with the development of distant metastasis.<br />Conclusion: The results of the study show that the NF-kappaB p65 protein is a significant predictor of survival in laryngeal carcinoma patients.

Details

Language :
Chinese
ISSN :
2096-7993
Volume :
21
Issue :
15
Database :
MEDLINE
Journal :
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
Publication Type :
Academic Journal
Accession number :
17969521