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Antifungal activity of cinnamaldehyde and eugenol congeners against wood-rot fungi.
- Source :
-
Bioresource technology [Bioresour Technol] 2008 Jul; Vol. 99 (11), pp. 5145-9. Date of Electronic Publication: 2007 Oct 22. - Publication Year :
- 2008
-
Abstract
- In this study, the antifungal activities of cinnamaldehyde and eugenol congeners against white-rot fungus Lenzites betulina and brown-rot fungus Laetiporus sulphureus were evaluated and the relationships between the antifungal activity and the chemical structures were also examined. Results from antifungal tests revealed that cinnamaldehyde, alpha-methyl cinnamaldehyde, (E)-2-methylcinnamic acid, eugenol and isoeugenol exhibited strong antifungal activity against all fungi tested. Results derived from the chemical structure-antifungal activity relationship study suggested that compounds with an aldehyde group or an acid group, a conjugated double bond and a length of CH chain outside the ring affect their antifungal properties. Furthermore, the presence of the methyl moiety in the ortho position may have a considerable influence on the inhibitory action against L. betulina and L. sulphureus. In addition, the lipophilicity may play, in part, a crucial role in determining the toxicity of phenylpropenes.
Details
- Language :
- English
- ISSN :
- 0960-8524
- Volume :
- 99
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Bioresource technology
- Publication Type :
- Academic Journal
- Accession number :
- 17945485
- Full Text :
- https://doi.org/10.1016/j.biortech.2007.09.013