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[Effects of Porphyromonas gingivalis lipopolysaccharide on collagen phagocytosis by human periodontal ligament fibroblasts].
- Source :
-
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology [Hua Xi Kou Qiang Yi Xue Za Zhi] 2007 Aug; Vol. 25 (4), pp. 339-41. - Publication Year :
- 2007
-
Abstract
- Objective: To investigate the effects of Porphyromonas gingivalis (P. gingivalis) lipopolysaccharide (LPS) on collagen phagocytosis of human periodontal ligament fibroblasts (hPDLF).<br />Methods: Fluorescence localization and flow cytometry was used to test the collagen phygocytosis of hPDLF stimulated by the various concentration of LPS for 48 hours in vitro.<br />Results: The collagen phygocytosis of hPDLF was increased significantly by 0.1 microg/mL LPS (P < 0.05).<br />Conclusion: This study indicates that P. gingivalis LPS may enhance the degradation of collagen by stimulating the phagocytic activity of the hPDLF in periodontitis.
Details
- Language :
- Chinese
- ISSN :
- 1000-1182
- Volume :
- 25
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
- Publication Type :
- Academic Journal
- Accession number :
- 17896486