CMP-pseudaminic acid is a natural potent inhibitor of PseB, the first enzyme of the pseudaminic acid pathway in Campylobacter jejuni and Helicobacter pylori.

Authors :: McNally DJ
Schoenhofen IC
Houliston RS
Khieu NH
Whitfield DM
Logan SM
Jarrell HC
Brisson JR
Source :: ChemMedChem [ChemMedChem] 2008 Jan; Vol. 3 (1), pp. 55-9.
Publication Year :: 2008

Subjects :: Anti-Bacterial Agents chemistry
Binding Sites
Campylobacter jejuni enzymology
Catalysis
Cytidine Monophosphate chemistry
Dose-Response Relationship, Drug
Enzyme Inhibitors chemistry
Helicobacter pylori enzymology
Magnetic Resonance Spectroscopy
Sialic Acids chemistry
Sialic Acids metabolism
Sugar Acids chemistry
Anti-Bacterial Agents pharmacology
Campylobacter jejuni drug effects
Cytidine Monophosphate pharmacology
Enzyme Inhibitors pharmacology
Helicobacter pylori drug effects
Sugar Acids pharmacology

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