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PET kinetic analysis: wavelet denoising of dynamic PET data with application to parametric imaging.
- Source :
-
Annals of nuclear medicine [Ann Nucl Med] 2007 Sep; Vol. 21 (7), pp. 379-86. Date of Electronic Publication: 2007 Sep 25. - Publication Year :
- 2007
-
Abstract
- Physiological functions (e.g., cerebral blood flow, glucose metabolism, and neuroreceptor binding) can be investigated as parameters estimated by kinetic modeling using dynamic positron emission tomography (PET) images. Imaging of these physiological parameters, called parametric imaging, can locate the regional distribution of functionalities. However, the most serious technical issue affecting parametric imaging is noise in dynamic PET data. This review describes wavelet denoising of dynamic PET images for improving image quality in estimated parametric images. Wavelet denoising provides significantly improved quality directly to dynamic PET images and indirectly to estimated parametric images. The application of wavelet denoising to radio-ligand and kinetic analysis is still in the development stage, but even so, it is thought that wavelet techniques will have a substantial impact on nuclear medicine in the near future.
- Subjects :
- Algorithms
Animals
Artifacts
Brain Mapping methods
Cluster Analysis
Computer Simulation
Coronary Circulation physiology
Fourier Analysis
Humans
Image Interpretation, Computer-Assisted methods
Image Processing, Computer-Assisted statistics & numerical data
Image Processing, Computer-Assisted trends
Kinetics
Nonlinear Dynamics
Nuclear Medicine statistics & numerical data
Nuclear Medicine trends
Positron-Emission Tomography statistics & numerical data
Radiopharmaceuticals pharmacokinetics
Time Factors
Image Enhancement methods
Positron-Emission Tomography methods
Software
Subjects
Details
- Language :
- English
- ISSN :
- 0914-7187
- Volume :
- 21
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Annals of nuclear medicine
- Publication Type :
- Academic Journal
- Accession number :
- 17876550
- Full Text :
- https://doi.org/10.1007/s12149-007-0044-9