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[Systemic therapy in children and adolescents].
- Source :
-
Der Urologe. Ausg. A [Urologe A] 2007 Oct; Vol. 46 (10), pp. 1404-6. - Publication Year :
- 2007
-
Abstract
- Urologic malignancies in childhood and adolescence are mainly nephroblastomas, neuroblastomas, soft tissue sarcomas, and germ cell tumors. National and supranational treatment studies are the standard of care for pediatric cancer in Germany; they yield 5-year survival rates of almost 90% for nephroblastoma and germ cell tumors and 60% for neuroblastoma (all stages) and rhabdomyosarcoma. The principles of antineoplastic therapy are the same as in adult cancer medicine; the drugs used depend upon the disease. In a multimodal treatment strategy, the role of chemotherapy as well as that of surgery and radiotherapy can differ, as is described for nephroblastoma, infant neuroblastoma, and stage 4 neuroblastoma.
- Subjects :
- Adolescent
Adrenal Gland Neoplasms drug therapy
Adrenal Gland Neoplasms mortality
Adrenal Gland Neoplasms pathology
Adrenal Gland Neoplasms surgery
Adrenal Medulla
Antineoplastic Combined Chemotherapy Protocols adverse effects
Chemotherapy, Adjuvant
Child
Child, Preschool
Combined Modality Therapy
Humans
Infant
Kidney Neoplasms drug therapy
Kidney Neoplasms mortality
Kidney Neoplasms pathology
Kidney Neoplasms surgery
Neoplasm Staging
Neoplasms, Germ Cell and Embryonal drug therapy
Neoplasms, Germ Cell and Embryonal mortality
Neoplasms, Germ Cell and Embryonal pathology
Neoplasms, Germ Cell and Embryonal surgery
Neuroblastoma drug therapy
Neuroblastoma mortality
Neuroblastoma pathology
Neuroblastoma surgery
Prognosis
Radiotherapy, Adjuvant
Rhabdomyosarcoma drug therapy
Rhabdomyosarcoma mortality
Rhabdomyosarcoma pathology
Rhabdomyosarcoma surgery
Survival Rate
Urogenital Neoplasms mortality
Urogenital Neoplasms pathology
Urogenital Neoplasms surgery
Wilms Tumor drug therapy
Wilms Tumor mortality
Wilms Tumor pathology
Wilms Tumor surgery
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Neoadjuvant Therapy
Urogenital Neoplasms drug therapy
Subjects
Details
- Language :
- German
- ISSN :
- 0340-2592
- Volume :
- 46
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Der Urologe. Ausg. A
- Publication Type :
- Academic Journal
- Accession number :
- 17823786
- Full Text :
- https://doi.org/10.1007/s00120-007-1541-0