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How hair gets its pigment.
- Source :
-
Cell [Cell] 2007 Sep 07; Vol. 130 (5), pp. 779-81. - Publication Year :
- 2007
-
Abstract
- Mutations in the transcription factor Foxn1 cause the nude phenotype in mice, which is characterized by a lack of visible hair. New work by Weiner et al. (2007) in this issue of Cell now shows that Foxn1 also contributes to hair color by marking which cells are to receive pigment from melanocytes.
- Subjects :
- Animals
Antibodies
Cell Differentiation
Cell Movement
Cell Proliferation
Fibroblast Growth Factor 2 genetics
Fibroblast Growth Factor 2 immunology
Forkhead Transcription Factors deficiency
Forkhead Transcription Factors genetics
Hair Follicle metabolism
Humans
Keratin-15
Keratin-5 genetics
Mice
Mice, Nude
Mice, Transgenic
Phenotype
Promoter Regions, Genetic
RNA, Messenger metabolism
Skin cytology
Skin growth & development
Skin Pigmentation physiology
Time Factors
Transcription, Genetic
Fibroblast Growth Factor 2 metabolism
Forkhead Transcription Factors metabolism
Hair Color physiology
Keratinocytes metabolism
Melanins metabolism
Melanocytes metabolism
Signal Transduction
Skin metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 0092-8674
- Volume :
- 130
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Cell
- Publication Type :
- Academic Journal
- Accession number :
- 17803901
- Full Text :
- https://doi.org/10.1016/j.cell.2007.08.032