Back to Search
Start Over
Duodeno-jejunal junction dyssynergia: description of a novel syndrome.
- Source :
-
World journal of gastroenterology [World J Gastroenterol] 2007 Aug 14; Vol. 13 (30), pp. 4112-6. - Publication Year :
- 2007
-
Abstract
- Aim: To investigate the hypothesis that duodeno-jejunal dyssynergia existed at the duodeno-jejunal junction.<br />Methods: Of 112 patients who complained of epigastric distension and discomfort after meals, we encountered nine patients in whom the duodeno-jejunal junction did not open on duodenal contraction. Seven healthy volunteers were included in the study. A condom which was inserted into the 1st duodenum was filled up to 10 mL with saline in increments of 2 mL and pressure response to duodenal distension was recorded from the duodenum, duodeno-jejunal junction and the jejunum.<br />Results: In healthy volunteers, duodenal distension with 2 and 4 mL did not produce pressure changes, while 6 and up to 10 mL distension effected significant duodenal pressure increase, duodeno-jejunal junction pressure decrease but no jejunal pressure change. In patients, resting pressure and duodeno-jejunal junction and jejunal pressure response to 2 and 4 mL duodenal distension were similar to those of healthy volunteers. Six and up to 10 mL 1st duodenal distension produced significant duodenal and duodeno-jejunal junction pressure increase and no jejunal pressure change.<br />Conclusion: Duodeno-jejunal junction failed to open on duodenal contraction, a condition we call 'duodeno-jejunal junction dyssynergia syndrome' which probably leads to stagnation of chyme in the duodenum and explains patients' manifestations.
- Subjects :
- Adult
Ataxia diagnosis
Case-Control Studies
Duodenal Diseases diagnosis
Duodenal Diseases physiopathology
Female
Gastrointestinal Diseases diagnosis
Gastrointestinal Diseases physiopathology
Humans
Jejunal Diseases diagnosis
Jejunal Diseases physiopathology
Male
Syndrome
Ataxia physiopathology
Duodenum physiopathology
Gastrointestinal Motility physiology
Jejunum physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 1007-9327
- Volume :
- 13
- Issue :
- 30
- Database :
- MEDLINE
- Journal :
- World journal of gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 17696232
- Full Text :
- https://doi.org/10.3748/wjg.v13.i30.4112