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Dynamic Sox5 protein expression during cranial ganglia development.
- Source :
-
Developmental dynamics : an official publication of the American Association of Anatomists [Dev Dyn] 2007 Sep; Vol. 236 (9), pp. 2702-7. - Publication Year :
- 2007
-
Abstract
- Sox5 is a member of the SoxD group of HMG-box transcription factors that, during the early stages of development, promotes neural crest generation. However, little is known about Sox5 function in neural crest derivatives such as the peripheral sensory nervous system. We have analysed the embryonic expression of Sox5 during chick cranial ganglia development, from the stages of ganglia condensation to those of differentiation. During this period, Sox5 expression is maintained in the crest-derived satellite glial cells in all the cranial ganglia. In contrast, Sox5 is only transiently expressed in a subpopulation of differentiating neurons of both neural crest and placode origin. This detailed analysis provides a good base to dissect the possible role of Sox5 in neural cell fate determination by future functional approaches.<br /> ((c) 2007 Wiley-Liss, Inc.)
- Subjects :
- Animals
Cell Differentiation
Cell Lineage
Chick Embryo
DNA-Binding Proteins biosynthesis
Gene Expression Profiling
High Mobility Group Proteins biosynthesis
Immunohistochemistry
Neural Crest embryology
SOXE Transcription Factors
Transcription Factors biosynthesis
Trigeminal Ganglion embryology
Brain embryology
Ganglia embryology
Gene Expression Regulation, Developmental
HMGB Proteins biosynthesis
HMGB Proteins genetics
Neuroglia metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1058-8388
- Volume :
- 236
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Developmental dynamics : an official publication of the American Association of Anatomists
- Publication Type :
- Academic Journal
- Accession number :
- 17685482
- Full Text :
- https://doi.org/10.1002/dvdy.21282