[Viral infection of herpes simplex, Epstein-Barr, varicela zoster, human papilloma, cytomegalovirus, or adenovirus are not related to sinonasal adenocarcinomas].

Authors :: Pérez Escuredo J
Llorente JL
Melón S
de Oña M
García Martínez J
Alvarez Marcos C
Hermsen M
Source :: Acta otorrinolaringologica espanola [Acta Otorrinolaringol Esp] 2007 Aug-Sep; Vol. 58 (7), pp. 311-5.
Publication Year :: 2007
Abstract: Objective: Several types of virus have been implicated in the development of head and neck tumors. However, until now sinonasal adenocarcinomas (ACN) have not been studied. The aim of this study is to screen a series of ACN for the presence of a number of viruses known to play a role in cancer.<br />Material and Method: Viral DNA sequences of herpes simplex virus, Epstein-Barr, varicela zoster, human papilloma, cytomegalovirus, and adenovirus were analysed by PCR in 37 primary ACN.<br />Results: Three tumors (8.1%) were positive for Epstein-Barr virus and 1 case (2.7%) for cytomegalovirus.<br />Conclusions: Viral infections do not seem to play a role in the etiology of ACN.

Subjects :: Adenocarcinoma pathology
Aged
Aged, 80 and over
DNA, Viral analysis
Female
Humans
Male
Middle Aged
Paranasal Sinus Neoplasms pathology
Polymerase Chain Reaction
Prevalence
Adenocarcinoma virology
Adenoviridae Infections genetics
Epstein-Barr Virus Infections genetics
Herpes Simplex genetics
Herpes Zoster genetics
Papillomavirus Infections genetics
Paranasal Sinus Neoplasms virology

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