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Ipomoeassin F, a new cytotoxic macrocyclic glycoresin from the leaves of Ipomoea squamosa from the Suriname rainforest.
- Source :
-
Natural product research [Nat Prod Res] 2007 Aug; Vol. 21 (10), pp. 872-6. - Publication Year :
- 2007
-
Abstract
- A new cytotoxic macrocyclic glycoresin, ipomoeassin F (6), has been isolated from the leaves of Ipomoea squamosa. The structure was elucidated by the interpretation of spectral data. Compound 6 was strongly active in the A2780 (human ovarian cancer cell line) assay with an IC(50) value of 0.036 microM.
- Subjects :
- Antineoplastic Agents, Phytogenic administration & dosage
Antineoplastic Agents, Phytogenic chemistry
Antineoplastic Agents, Phytogenic therapeutic use
Cell Line, Tumor drug effects
Humans
Inhibitory Concentration 50
Plant Extracts administration & dosage
Plant Extracts chemistry
Plant Extracts therapeutic use
Plant Leaves
Suriname
Antineoplastic Agents, Phytogenic pharmacology
Glycoconjugates administration & dosage
Glycoconjugates chemistry
Glycoconjugates pharmacology
Glycoconjugates therapeutic use
Ipomoea
Phytotherapy
Plant Extracts pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 1478-6419
- Volume :
- 21
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Natural product research
- Publication Type :
- Academic Journal
- Accession number :
- 17680496
- Full Text :
- https://doi.org/10.1080/14786410600929576