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[Effect of biologically active food supplement coenzyme Q10 on metabolic processes in the myocardium of rats kept in different temperature conditions].
- Source :
-
Voprosy pitaniia [Vopr Pitan] 2007; Vol. 76 (3), pp. 19-23. - Publication Year :
- 2007
-
Abstract
- In present research the action of coenzyme Q10 on energetic metabolism and antioxidant system at different temperature conditions has been studied. It was established that the addition of coenzyme Q10 caused inadequate stimulation of main metabolic systems that could lead to running out of functional reserves of cardiomyocytes. The use of coenzyme Q10 helped to optimize intracellular compensating mechanisms supplying the defense of myocardium. Introduction in a diet coenzyme Q10 in conditions of a temperature's comfort threshold excess and development of a histic hypoxia can promote the decrease of gravity of hypoxic myocardium's lesions and to glycogenolysis' amplification that promotes maintenance of an energy homeostasis of a myocardium in posthypoxia term. It is possible to assume, that the augmentation of duration of reception coenzyme Q10 or its dosages can render more expressed protective effect.
- Subjects :
- Animals
Coenzymes administration & dosage
Coenzymes pharmacology
Disease Models, Animal
Housing, Animal
Male
Rats
Temperature
Ubiquinone administration & dosage
Ubiquinone pharmacology
Adaptation, Physiological
Dietary Supplements
Energy Metabolism drug effects
Hypoxia metabolism
Hypoxia physiopathology
Myocardium enzymology
Myocardium metabolism
Ubiquinone analogs & derivatives
Subjects
Details
- Language :
- Russian
- ISSN :
- 0042-8833
- Volume :
- 76
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Voprosy pitaniia
- Publication Type :
- Academic Journal
- Accession number :
- 17674515