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A novel method of multisite atrial pacing, incorporating Bachmann's bundle area and coronary sinus ostium, for electrical atrial resynchronization in patients with recurrent atrial fibrillation.
- Source :
-
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology [Europace] 2007 Sep; Vol. 9 (9), pp. 805-11. Date of Electronic Publication: 2007 Aug 01. - Publication Year :
- 2007
-
Abstract
- Aims: The aim of the study was to assess efficacy and safety of a novel method of multisite atrial pacing, incorporating Bachmann's bundle (BB) and coronary sinus (CS) ostium pacing, which was implemented for the first time in atrial fibrillation (AF) patients with intra-atrial conduction delay.<br />Methods and Results: This follow-up study included 97 patients with drug refractory symptomatic AF, sinus node dysfunction, sinus P-wave > or = 120 ms, and normal atrioventricular conduction. Pacing efficacy was assessed on the basis of two main endpoints: successful rhythm control and the absence of documented or symptomatic AF. During the mean 2.3 +/- 0.7 years of follow-up, the survival rate was 99%, pacing maintenance rate 97%, and the need for re-operation 5%. Rhythm control efficacy was 90%, and 14 patients had no evidence of recurrent AF. After implantation, the mean number of anti-arrhythmic drugs used (P < 0.0001), the need for cardioversion (P < 0.01), and the incidence (P < 0.0001) and duration (P < 0.001) of AF-related hospitalizations decreased. P-wave duration with multisite atrial pacing was shorter than during sinus rhythm, BB, and CS pacing (P < 0.0001).<br />Conclusion: A novel method of multisite atrial pacing is safe, provides effective long-term rhythm control, and decreases the necessity for adjunctive therapies in patients with refractory AF and intra-atrial conduction delay.
- Subjects :
- Adult
Aged
Aged, 80 and over
Anti-Arrhythmia Agents therapeutic use
Atrial Fibrillation complications
Atrial Fibrillation drug therapy
Catheter Ablation
Electrocardiography methods
Female
Follow-Up Studies
Heart Conduction System
Humans
Male
Middle Aged
Pacemaker, Artificial
Time Factors
Atrial Fibrillation diagnosis
Atrial Fibrillation prevention & control
Atrial Fibrillation therapy
Cardiac Pacing, Artificial methods
Coronary Sinus pathology
Electrophysiologic Techniques, Cardiac methods
Heart Atria pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1099-5129
- Volume :
- 9
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 17670780
- Full Text :
- https://doi.org/10.1093/europace/eum152