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Impaired emotional categorisation in young people at increased familial risk of depression.
- Source :
-
Neuropsychologia [Neuropsychologia] 2007 Oct 01; Vol. 45 (13), pp. 2975-80. Date of Electronic Publication: 2007 Jun 09. - Publication Year :
- 2007
-
Abstract
- Negative biases in emotional information processing are characteristic of patients with acute depression and may persist after clinical recovery. It is not clear, however, whether such biases are present before the onset of the depressive disorder. The aim of the present study was to examine whether young people at risk of depression, by virtue of having a depressed biological parent (FH+), demonstrate negative biases in tasks of emotional facial recognition and emotional categorization. We also assessed whether task performance and the influence of parental depression are modified by allelic variation in the serotonin transporter (5HTT) gene. We found that the FH+ participants did not show evidence of negative biases relative to matched controls. They were, however, significantly slower to perform a task of emotional categorization. 5HTT genotype did not influence emotional processing significantly. We conclude that negative biases in emotional processing do not appear to be present in people with a family history of depression. However, impairment in emotional categorization could identify a high-risk phenotype and may indicate that people at genetic risk of depression have difficulty in using "mood as information".
- Subjects :
- Adolescent
Adult
Analysis of Variance
Association Learning physiology
Case-Control Studies
Chi-Square Distribution
Depressive Disorder, Major genetics
Disease Susceptibility
Facial Expression
Family
Female
Genetic Variation
Humans
Male
Matched-Pair Analysis
Pedigree
Risk Factors
Social Perception
Child of Impaired Parents
Depressive Disorder, Major psychology
Emotions physiology
Recognition, Psychology physiology
Serotonin Plasma Membrane Transport Proteins genetics
Subjects
Details
- Language :
- English
- ISSN :
- 0028-3932
- Volume :
- 45
- Issue :
- 13
- Database :
- MEDLINE
- Journal :
- Neuropsychologia
- Publication Type :
- Academic Journal
- Accession number :
- 17659308
- Full Text :
- https://doi.org/10.1016/j.neuropsychologia.2007.05.016